KYA1797 is a novel inhibitor of the Wnt/ss-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ss-catenin and Ras degradation through enhancement of the ss-catenin destruction complex activating GSK3ss, effectively suppressing the growth of CRCs harboring APC and KRAS mutations. References:
纯度:≥98%
CAS:851304-36-4