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重组β淀粉样前体蛋白结合蛋白2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组淀粉样蛋白β前体蛋白结合蛋白A2(APBA2)
Recombinant APBA2
产品介绍
基因名:

APBA2


产品别名:

D15S1518E; HsT16821; LIN-10; MGC:14091; MINT2; X11-BETA; X11L; APBA2; amyloid beta precursor protein binding family A member 2; amyloid beta precursor protein binding family A member 2; amyloid-beta A4 precursor protein-binding family A member 2; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; β淀粉样前体蛋白结合蛋白2; 淀粉样蛋白β前体蛋白结合蛋白A2(APBA2);


背景信息:
The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11 Alpha (also designated Mint 1), X11 Beta (Mint 2) and X11 Gamma(Mint 3).

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。