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重组多功能DNA修复酶蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组脱嘌呤/脱嘧啶核酸内切酶1(APEX1)蛋白
Recombinant APEX1
产品介绍
基因名:

APEX1


产品别名:

APE; APE1; APEN; APEX; APX; HAP1; REF1; APEX1; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endodeoxyribonuclease 1; DNA-(apurinic or apyrimidinic site) endonuclease; AP endonuclease class I; AP lyase; APEX nuclease (multifunctional DNA repair enzyme) 1; DNA-(apurinic or apyrimidinic site) lyase; apurinic-apyrimidinic endonuclease 1; apurinic/apyrimidinic (abasic) endonuclease; deoxyribonuclease (apurinic or apyrimidinic); protein REF-1; redox factor-1; 多功能DNA修复酶; 脱嘌呤/脱嘧啶核酸内切酶1(APEX1);


背景信息:
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete repair. APE1 stimulates the DNA binding activity of many transcription factors, which participate in cancer promotion and progression. APE1 regulates the redox state of multiple transcription factors, such as c-Jun, c-Fos, NF-kB, p53. APEN is also involved in calcium-dependent down-regulation of PTH expression.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。