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重组丝裂原活化蛋白激酶激酶8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化丝裂原活化蛋白激酶激酶8
Recombinant MAP3K8
产品介绍
基因名:

MAP3K8


产品别名:

AURA2; COT; EST; ESTF; MEKK8; TPL2; Tpl-2; c-COT; MAP3K8; mitogen-activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Ewing sarcoma transformant; augmented in rheumatoid arthritis 2; cot (cancer Osaka thyroid) oncogene; proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; tumor progression locus 2; 丝裂原活化蛋白激酶激酶8; 磷酸化丝裂原活化蛋白激酶激酶8;


背景信息:
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。