Sch-32615 (the S,S-diastereomer) is a novel and potent inhibitor of enkephalinase, an enzyme responsible for the degradation of endogenous enkephalins. The administration of SCH 32615 (3 mg/kg) decreased both D-1 and D-2 antagonist-induced catalepsy. In contrast, SCH 32615 (0.3 mg/kg) increased D-1 agonist-induced non-stereotyped grooming and D-2 agonist-induced stereotypies. SCH 32615 competitively antagonizes enkephalinase in vitro and produces analgesia in vivo.

纯度：≥98%

CAS：83861-02-3