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重组羟基类固醇(17β)脱氢酶4/17β-HSD4蛋白
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant HSD17B4
Recombinant hydroxysteroid 17-beta dehydrogenase 4 protein
产品介绍
基因名：

HSD17B4


产品别名：

DBP； MFE-2； MFP-2； MPF-2； PRLTS1； SDR8C1； HSD17B4； hydroxysteroid 17-beta dehydrogenase 4； hydroxysteroid 17-beta dehydrogenase 4； peroxisomal multifunctional enzyme type 2； 17-beta-HSD 4； 17-beta-HSD IV； 17-beta-hydroxysteroid dehydrogenase 4； 17beta-estradiol dehydrogenase type IV； 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase； D-3-hydroxyacyl-CoA dehydratase； D-bifunctional protein, peroxisomal； beta-hydroxyacyl dehydrogenase； beta-keto-reductase； epididymis secretory sperm binding protein； hydroxysteroid dehydrogenase 4； multifunctional protein 2； peroxisomal multifunctional protein 2； short chain dehydrogenase/reductase family 8C member 1； 羟基类固醇(17β)脱氢酶4/17β-HSD4；


背景信息：
17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。