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重组钙激活钾通道蛋白β1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant KCNMB1
Recombinant potassium calcium-activated channel subfamily M regulatory beta subunit 1 protein
产品介绍
基因名：

KCNMB1


产品别名：

BKbeta1； K(VCA)beta； SLO-BETA； hbeta1； hslo-beta； k(VCA)beta-1； slo-beta-1； KCNMB1； potassium calcium-activated channel subfamily M regulatory beta subunit 1； potassium calcium-activated channel subfamily M regulatory beta subunit 1； calcium-activated potassium channel subunit beta-1； BK channel beta subunit 1； BK channel subunit beta-1； MaxiK channel beta-subunit 1； big potassium channel beta subunit 1； calcium-activated potassium channel, subfamily M subunit beta-1； charybdotoxin receptor subunit beta-1； large conductance Ca2+-activated K+ channel beta 1 subunit； maxi K channel subunit beta-1； potassium channel subfamily M regulatory beta subunit 1； potassium large conductance calcium-activated channel, subfamily M, beta member 1； 钙激活钾通道蛋白β1；


背景信息：
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。