Uridine triphosphate, formerly known as INS-316; KRN-316; UTP, is a purinoceptor P2U agonist potentially for the treatment of lung cancer. Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor. Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y2 receptors. Uridine triphosphate prolongs action potential duration of guinea pig papillary muscles via P2Y2 purinoceptors. References: Kam WR, Liu Y, Ding J, Sullivan DA. Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells? Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4287-94. doi: 10.1167/iovs.16-19937. PubMed PMID: 27552406; PubMed Central PMCID: PMC5015965.

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CAS：63-39-8