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重组卵白蛋白(OVA)天然蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组纤溶酶原激活物抑制因子2(PAI2)蛋白
Recombinant SERPINB2
产品介绍
基因名:

SERPINB2


产品别名:

HsT1201; PAI; PAI-2; PAI2; PLANH2; SERPINB2; serpin family B member 2; serpin family B member 2; plasminogen activator inhibitor 2; monocyte Arg-serpin; placental plasminogen activator inhibitor; plasminogen activator inhibitor, type II (arginine-serpin); plasminogen-activator inhibitor; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serpin B2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; urokinase inhibitor; 卵白蛋白(OVA)天然蛋白; 纤溶酶原激活物抑制因子2(PAI2); 纤溶酶原激活物抑制因子2/血浆酶原激活酶抑制因子-2;


背景信息:
SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin.
SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。