基因名：
PDHA1
产品别名：
E1alpha； PDHA； PDHAD； PDHCE1A； PHE1A； PDHA1； pyruvate dehydrogenase E1 subunit alpha 1； pyruvate dehydrogenase E1 subunit alpha 1； pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial； PDHE1-A type I； pyruvate dehydrogenase (lipoamide) alpha 1； pyruvate dehydrogenase E1 alpha 1 subunit； pyruvate dehydrogenase alpha 1； pyruvate dehydrogenase complex, E1-alpha polypeptide 1； 丙酮酸脱氢酶α(PDHA1)； 丙酮酸脱氢酶α1； 磷酸化丙酮酸脱氢酶α1；
背景信息：
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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