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重组丝裂原激活蛋白激酶10(MAPK10)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组氨基末端激酶3蛋白
Recombinant MAPK10
产品介绍
基因名:

MAPK10


产品别名:

JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK; MAPK10; mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; JNK3 alpha protein kinase; MAP kinase 10; MAP kinase p49 3F12; c-Jun N-terminal kinase 3; stress activated protein kinase beta; stress-activated protein kinase 1b; stress-activated protein kinase JNK3; 丝裂原激活蛋白激酶10(MAPK10); 氨基末端激酶3;


背景信息:
MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。