基因名:
SEL1L
产品别名:
Hrd3; PRO1063; SEL1-LIKE; SEL1L1; SEL1L; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; protein sel-1 homolog 1; SEL1L, ERAD E3 ligase adaptor subunit; Suppressor of lin 12 (sel-1), C. elegans, homolog of; sel-1 suppressor of lin-12-like 1; suppressor of lin-12-like protein 1;
背景信息:
SEL1L, highly similar to the C elegans sel-1 gene, is a recently cloned human gene whose function is under investigation. SEL1L is differentially expressed in tumors and normal tissues and seems to play a role in tumor growth and aggressiveness. It may be an important negative regulator of the "notch" pathway which acts as a key regulator of the cellular proliferation and specification processes in both vertebrates and invertebrates. SEL1L may function in the protein degradation processes through the ubiquitin-proteosome system and perhaps in regulating important pathways such TGF-beta.
It is ubiquitously expressed only in fetal and neoplastic tissues. In normal adult tissues is highly expressed in the acini and in the alpha cells of the pancreas; in general it is highly represented in secretory cells such as plasma cells.
标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。