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重组丝氨酸肽酶抑制因子Kazal型1(SPINK1)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组肿瘤相关胰蛋白酶抑制剂1
Recombinant SPINK1
产品介绍
基因名:

SPINK1


产品别名:

PCTT; PSTI; Spink3; TATI; TCP; SPINK1; serine peptidase inhibitor Kazal type 1; serine peptidase inhibitor Kazal type 1; serine protease inhibitor Kazal-type 1; pancreatic secretory trypsin inhibitor; serine protease inhibitor, Kazal type 1; tumor-associated trypsin inhibitor; 丝氨酸肽酶抑制因子Kazal型1(SPINK1); 肿瘤相关胰蛋白酶抑制剂1;


背景信息:
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE as well as cancerous prostate cells. The research result indicated that the potential of SPINK1 as an extracellular therapeutic target in prostate cancer. In contrast, knockdown of SPINK1 in 22RV1 cells inhibited cell proliferation, cell invasion, and tumor growth in xenograft assays.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。