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重组T-细胞急性淋巴细胞白血病蛋白1(TAL1)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组T细胞急性淋巴细胞白血病蛋白1
Recombinant TAL1
产品介绍
基因名:

TAL1


产品别名:

SCL; TCL5; bHLHa17; tal-1; TAL1; TAL bHLH transcription factor 1, erythroid differentiation factor; TAL bHLH transcription factor 1, erythroid differentiation factor; T-cell acute lymphocytic leukemia protein 1; T-cell acute lymphocytic leukemia 1; T-cell leukemia/lymphoma protein 5; class A basic helix-loop-helix protein 17; stem cell protein; tal-1 product; T-细胞急性淋巴细胞白血病蛋白1(TAL1); T细胞急性淋巴细胞白血病蛋白1;


背景信息:
Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。