基因名：
TCF3
产品别名：
AGM8； AGM8A； AGM8B； E2A； E47； ITF1； TCF-3； VDIR； bHLHb21； p75； TCF3； transcription factor 3； transcription factor 3； transcription factor E2-alpha； E2A-HLF fusion transcript protein； NOL1-TCF3 fusion； VDR interacting repressor； class B basic helix-loop-helix protein 21； helix-loop-helix protein HE47； immunoglobulin transcription factor 1； kappa-E2-binding factor； negative vitamin D response element-binding protein； transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)； transcription factor ITF-1； vitamin D receptor-interacting repressor； 免疫球蛋白转录因子1(ITF1)； 磷酸化转录因子3； 转录因子3；
背景信息：
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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