GPP78, formerly known as CAY10618, is a NMPRTase Inhibitor. The inhibition of NAD synthesis or salvage pathways has been proposed as a novel target for antitumorally bioavailable drugs. GPP78 exhibits an IC(50) for cytotoxicity in vitro of 3.8 +/- 0.3 nM and an IC(50) for NAD depletion of 3.0 +/- 0.4 nM. References:
纯度:≥98%
CAS:1202580-59-3