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重组细胞因子信号传导抑制蛋白1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组细胞因子信号转导抑制因子1(SOCS1)蛋白
Recombinant SOCS1
产品介绍
基因名:

SOCS1


产品别名:

AISIMD; CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3; SOCS1; suppressor of cytokine signaling 1; suppressor of cytokine signaling 1; suppressor of cytokine signaling 1; JAK binding protein; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Tec-interacting protein 3; cytokine-inducible SH2 protein 1; 细胞因子信号传导抑制蛋白1; 细胞因子信号转导抑制因子1(SOCS1);


背景信息:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity (By similarity). Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor(LIF). Regulates interferon-gamma mediated sensory neuron survival. Implicated, through SOCS box binding, in ubiquitin-dependent protein degradation. High expression in thymus. Lower expression in lung and spleen.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。