JX-401 is a p38alpha inhibitor containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. References: Friedmann Y, Shriki A, Bennett ER, Golos S, Diskin R, Marbach I, Bengal E, Engelberg D. JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol. 2006 Oct;70(4):1395-405. Epub 2006 Jul 17. PubMed PMID: 16847144.
纯度:≥98%
CAS:349087-34-9