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重组孕激素受体膜相关元件蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant PGRMC1
Recombinant progesterone receptor membrane component 1 protein
产品介绍
基因名:

PGRMC1


产品别名:

Dap1; HPR6.6; IZA; MPR; PGRMC1; progesterone receptor membrane component 1; progesterone receptor membrane component 1; membrane-associated progesterone receptor component 1; progesterone binding protein; 孕激素受体膜相关元件;


背景信息:
PGRMC1 is a progesterone receptor component of 195 aa with a 26 residue N terminal hydrophobic region and no N terminal glycosylation site. It has an overall homology of 50% with PGRMC2 but their C terminal regions have a 68% homology, including a highly conserved 58 residue sequence.PGRMC1 is a heme bind proteins that is up-regulated in several cancers. In breast tumors, PGRMC1 is associated with hypoxia estrogen receptor-negative status. PGRMC1 is also shown to stimulate AKT phosphorylation and is known to stabilise the EGFR receptor tyrosine kinase.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。