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重组DNA拓扑异构酶2结合蛋白1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组拓扑异构酶Ⅱ结合蛋白1(TOPBP1)
Recombinant TOPBP1
产品介绍
基因名:

TOPBP1


产品别名:

Dpb11; TOP2BP1; TOPBP1; DNA topoisomerase II binding protein 1; DNA topoisomerase II binding protein 1; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; topoisomerase (DNA) II binding protein 1; DNA拓扑异构酶2结合蛋白1; 拓扑异构酶Ⅱ结合蛋白1(TOPBP1);


背景信息:
Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。