重组磷酸化DDX58蛋白

立即咨询

重组磷酸化DDX58蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant RIGI
Recombinant RNA sensor RIG-I protein

产品介绍

基因名：

RIGI

产品别名：

DDX58； RIG-I； RIG1； RLR-1； SGMRT2； RIGI； RNA sensor RIG-I； RNA sensor RIG-I； antiviral innate immune response receptor RIG-I； ATP-dependent RNA helicase DDX58； DEAD (Asp-Glu-Ala-Asp) box polypeptide 58； DEAD box protein 58； DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide； DExD/H-box helicase 58； RNA helicase RIG-I； probable ATP-dependent RNA helicase DDX58； retinoic acid-inducible gene 1 protein； retinoic acid-inducible gene I protein；磷酸化DDX58；

背景信息：

The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG1/DDX58) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG1/DDX58 activates the kinases TBK1 and IKKe through the adaptor protein IPS1. These kinases then phosphorylate the transcription factors IRF3 and IRF7 which are essential for the expression of type-I interferons. RIG1/DDX58 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。