JNJ-7777120 is a potent and selective non-imidazole H4R antagonist with Ki of 4 ±1 nM, it was identified from a high throughput screen of Johnson & Johnson Pharmaceutical Research and Development's corporate compound collection. JNJ-7777120 is the first potent and selective non-imidazole antagonist of histamine H4 receptor (H4R) with Ki of 4.5 nM. JNJ 7777120 binds with high affinity to the H4 receptor and has a greater than 1000-fold selectivity over the other histamine receptors. JNJ 7777120 is a selective and potent H4 receptor antagonist with little or no affinity for over 50 other targets.

纯度：≥98%