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重组IL-1相关Ig受体蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组单Ig IL1相关受体(SIGIRR)蛋白
Recombinant Sigirr
产品介绍
基因名:

Sigirr


产品别名:

AI256711; TIR8; Sigirr; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single Ig IL-1 receptor related protein; single Ig IL-1R-related molecule; single Ig IL-1R-related protein; single immunoglobulin domain-containing IL1R-related protein; toll/interleukin-1 receptor 8; IL-1相关Ig受体; 单Ig IL1相关受体(SIGIRR);


背景信息:
Single Ig IL-1-related receptor SIGIRR, also designated single immunoglobulin domain-containing IL-1R-related protein or Toll/interleukin-1 receptor 8 (TIR8), is a member of the interleukin-1 receptor family. SIGIRR acts as a negative regulator of the IL-1R and Toll-like receptor signaling pathways and reduces the recruitment of certain components to the TLR4 receptor. Subsequently, SIGIRR confers resistance to P. aeruginosa corneal infection. SIGIRR can form complexes with IL-1R1, MYD-88, IRAK-1 and TRAF-6 upon IL-1 stimulation and TLR4 after LPS stimulation. It is a single-pass type III membrane protein that is mainly expressed in kidney, lung and gut.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。