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重组低密度脂蛋白受体的诱导降解蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant MYLIP
Recombinant myosin regulatory light chain interacting protein
产品介绍
基因名:

MYLIP


产品别名:

IDOL; MIR; MYLIP; myosin regulatory light chain interacting protein; myosin regulatory light chain interacting protein; E3 ubiquitin-protein ligase MYLIP; E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor; RING-type E3 ubiquitin transferase MYLIP; band 4.1 superfamily member BZF1; cellular modulator of immune recognition (c-MIR); inducible degrader of the LDL-receptor; 低密度脂蛋白受体的诱导降解蛋白;


背景信息:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。