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重组原肌球蛋白调节蛋白4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant TMOD4
Recombinant tropomodulin 4 protein
产品介绍
基因名:

TMOD4


产品别名:

SK-TMOD; TMOD4; tropomodulin 4; tropomodulin 4; tropomodulin-4; actin-capping protein; skeletal muscle tropomodulin; skeletal tropomodulin; tropomodulin 4 (muscle); 原肌球蛋白调节蛋白4;


背景信息:
Originally isolated from human erythrocytes, the tropomodulin (TMOD) family of proteins cap the pointed end of actin filaments (1,2). A component of the membrane skeleton, TMOD binds to the amino terminus of tropomyosin, which coats the surface of actin, and thus blocks the elongation and depolymerization of actin filaments (3,4). Four TMOD isoforms, TMOD1 - TMOD4, have been characterized in humans (2). TMOD expression is isoform-specific; TMOD3 is expressed ubiquitously, whereas TMOD2 and TMOD4 are expressed in neuronal tissue and muscle, respectively (5). TMOD4, which has a similar organization to TMOD2, is intergenically spliced by the putative transformation suppressor gene product YL-1 (1). The human TMOD4 gene maps to the telomeric end of chromosome 1q12, and encodes a 351 amino acid protein (1,5). The expression and chromosomal location of the TMOD4 gene make it a candidate for limb girdle musclular dystrophy 1B (5).

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。