重组棕榈酰化膜蛋白5

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重组棕榈酰化膜蛋白5

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

重组棕榈酰化膜蛋白5(MPP5)
Recombinant Pals1

产品介绍

基因名：

Pals1

产品别名：

3830420B02Rik； AI255216； AI644496； Mpp5； Pals1； protein associated with LIN7 1, MAGUK family member； protein associated with LIN7 1, MAGUK family member； protein PALS1； MAGUK p55 subfamily member 5； membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5)； membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)； protein associated with Lin-7 1；棕榈酰化膜蛋白5；棕榈酰化膜蛋白5(MPP5)；

背景信息：

Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。