J-113397 is a potent and selective NOP receptor antagonist (IC50 are 2.3, 1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively). J-113397 inhibits nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test. References: Scoto GM, Aricò G, Ronsisvalle S, Parenti C. Effects of intraplantar nocistatin and (±)-J 113397 injections on nociceptive behavior in a rat model of inflammation. Pharmacol Biochem Behav. 2012 Jan;100(3):639-44. doi: 10.1016/j.pbb.2011.11.007. PubMed PMID: 22120202.

纯度：≥98%

CAS：256640-45-6