KU-32 is a C-terminal inhibitor of Hsp90 which increases Hsp70 expression, and protects against neuronal glucotoxicity and reverses multiple clinical indices of diabetic peripheral neuropathy. References: Chatterjee BK, Jayaraj A, Kumar V, Blagg B, Davis RE, Jayaram B, Deep S, Chaudhuri TK. Stimulation of heat shock protein 90 chaperone function through binding of a novobiocin analog KU-32. J Biol Chem. 2019 Feb 21. pii: jbc.RA118.002502. doi: 10.1074/jbc.RA118.002502. [Epub ahead of print] PubMed PMID: 30792306.
纯度:≥98%
CAS:956498-70-7