JCP174-Et is a suicide substrate for serine proteases, irreversibly inactivating human leukocyte (HL) elastase, porcine pancreatic (PP) elastase, and chymotrypsin. References: Harper JW, Powers JC. Reaction of serine proteases with substituted 3-alkoxy-4-chloroisocoumarins and 3-alkoxy-7-amino-4-chloroisocoumarins: new reactive mechanism-based inhibitors. Biochemistry. 1985 Dec 3;24(25):7200-13. PubMed PMID: 3910097.
纯度:≥98%
CAS:24672-91-1