重组甲基样蛋白16

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重组甲基样蛋白16

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant Mettl16
Recombinant methyltransferase like 16 protein

产品介绍

基因名：

Mettl16

产品别名：

2610100D03Rik； 2810013M15Rik； A830095F14Rik； AI846133； Mett10d； Mettl16； methyltransferase like 16； methyltransferase like 16； RNA N6-adenosine-methyltransferase METTL16； N6-adenosine-methyltransferase METTL16； U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase； methyltransferase 10 domain containing； methyltransferase 10 domain-containing protein； methyltransferase-like protein 16； putative methyltransferase METT10D；甲基样蛋白16；

背景信息：

METT10D is a 562 amino acid protein that belongs to the METTL16/rlmF family and methyltransferase superfamily. A putative methyltransferase, METT10D exists as two alternatively spliced isoforms and undergoes phosphorylation in response to DNA damage, most likely by Atm or ATR. The gene encoding METT10D maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is linked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。