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重组前蛋白转化酶枯草溶菌素9(PCSK9)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组神经细胞凋亡调节转化蛋白1/前蛋白转化酶枯草溶菌素9
Recombinant Pcsk9
产品介绍
基因名:

Pcsk9


产品别名:

AI415265; AI747682; FH3; HCHOLA3; Narc1; PC9; Pcsk9; proprotein convertase subtilisin/kexin type 9; proprotein convertase subtilisin/kexin type 9; proprotein convertase subtilisin/kexin type 9; NARC-1; convertase subtilisin; neural apoptosis regulated convertase 1; proprotein convertase 9; proprotein convertase PC9; subtilisin/kexin-like protease PC9; 前蛋白转化酶枯草溶菌素9(PCSK9); 神经细胞凋亡调节转化蛋白1/前蛋白转化酶枯草溶菌素9;


背景信息:
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。