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JAK3i
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1918238-72-8
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

JAK3i is a selective covalent inhibitor of JAK3 kinase activity. It reveals two distinct temporally bioavailable waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation. References: Smith GA, Uchida K, Weiss A, Taunton J. Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nat Chem Biol. 2016 May;12(5):373-9. doi: 10.1038/nchembio.2056. Epub 2016 Mar 28. PubMed PMID: 27018889; PubMed Central PMCID: PMC4837022.

纯度:≥98%

CAS:1918238-72-8