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PFK-158
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PFK-158图片
CAS NO:1462249-75-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
PFK 158, PFK158, ACT-PEK-158
产品介绍

生物活性

PFK-158是6-磷酸果糖-2-激酶/果糖-2,6-双磷酸酶(PFK-2/FBPase)同工型3(PFKFB3)的抑制剂,是3-(3-吡啶基)-1-[4-吡啶基]-2-丙烯-1-酮(3PO),具有潜在的抗肿瘤活性。

化学数据

目录号A14398
作用机制Inhibitor (抑制剂)
M. Wt328.29
FormulaC18H11F3N2O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1462249-75-7
SynonymsPFK 158, PFK158, ACT-PEK-158
SMILESO=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2

溶解度

In vitroDMSO14 mg/mL (42.64 mM)
Water<1 mg/mL
Ethanol4 mg/mL (12.18 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM30.46 mL152.3 mL304.61 mL
0.5 mM6.09 mL30.46 mL60.92 mL
1 mM3.05 mL15.23 mL30.46 mL
5 mM0.61 mL3.05 mL6.09 mL

*The above data is based on the productmolecular weight 328.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.