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SNAP-8719
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:255893-38-0
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

SNAP-8719 is a selective α1D-AR antagonist. SNAP-8719 showed better selectivity for α1D-AR, with lower binding affinity for the 5-HT1A receptor. References: Sakauchi N, Kohara Y, Sato A, Suzaki T, Imai Y, Okabe Y, Imai S, Saikawa R, Nagabukuro H, Kuno H, Fujita H, Kamo I, Yoshida M. Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carb oxamide (TAK-259), as a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist with Anti-urinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities. J Med Chem. 2016 Mar 8. [Epub ahead of print] PubMed PMID: 26954848.

纯度:≥98%

CAS:255893-38-0