MBRI-001 is a deuterated form of plinabulin with potent anti-cancer activity. MBRI-001 demonstrated better pharmacokinetic properties than that of plinabulin. Additionally, its antitumor activity is in a low nanomolar level for a variety of cancer cell lines and high activity against human NCI-H460 xenograted in mice intravenous administration. Importantly, continuous administration of MBRI-001 exhibited lower toxicity compared to docetaxel.

纯度：≥98%

CAS：2054938-28-0