IMB-YH-8 is an inhibitor of protein kinase B (PknB), inhibiting PknB auto-phosphorylation and the phosphorylation of GarA by PknB in a dose-dependent manner. References: Xu J, Wang JX, Zhou JM, Xu CL, Huang B, Xing Y, Wang B, Luo R, Wang YC, You XF, Lu Y, Yu LY. A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity. Sci Rep. 2017 Jul 11;7(1):5093. doi: 10.1038/s41598-017-04108-7. PubMed PMID: 28698545; PubMed Central PMCID: PMC5506005.
纯度:≥98%
CAS:17615-10-0