IMC-76 is a BCL2 i-motif-interactive compound that acts by destabilizing or unfolding the i-motif. References: Kendrick S, Muranyi A, Gokhale V, Hurley LH, Rimsza LM. Simultaneous Drug Targeting of the Promoter MYC G-Quadruplex and BCL2 i-Motif in Diffuse Large B-Cell Lymphoma Delays Tumor Growth. J Med Chem. 2017 Aug 10;60(15):6587-6597. doi: 10.1021/acs.jmedchem.7b00298. Epub 2017 Jul 25. PubMed PMID: 28605593.
纯度:≥98%
CAS:98129-27-2