SPRC, formerly known as S-Propargyl-cysteine, is a novel synthetic molecule exerting antioxidant effects via elevating generation of endogenous H2S. SPRC activates Gp130-mediated STAT3 and prevents doxorubicin-induced cardiotoxicity. References: Liang YH, Shen YQ, Guo W, Zhu YZ. SPRC protects hypoxia and re-oxygenation injury by improving rat cardiac contractile function and intracellular calcium handling. Nitric Oxide. 2014 Sep 15;4113-9. doi: 10.1016/j.niox.2014.05.010. Epub 2014 Jun 2. PubMed PMID: 24887754.
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CAS:3262-64-4