SQ-29548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a Ki of 4.1 nM. SQ-29548 inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM. References: Singh J, Seth SD, Manchanda SC, Seth S. Protective actions of a thromboxane receptor antagonist, SQ 29548 on the ischemic myocardium: morphologic and hemodynamic effects. Prostaglandins Leukot Essent Fatty Acids. 1997 Feb;56(2):105-10. PubMed PMID: 9051718.

纯度：≥98%

CAS：98672-91-4