SR 2640 hydrochloride is a potent and selective competitive leukotriene D4 and E4 receptor antagonist. SR 2640 hydrochloride inhibits LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). References: Di Capite J, Shirley A, Nelson C, Bates G, Parekh AB. Intercellular Ca2+ wave propagation involving positive feedback between CRAC channels and cysteinyl leukotrienes. FASEB J. 2009 Mar;23(3):894-905. doi: 10.1096/fj.08-118935. Epub 2008 Oct 31. PubMed PMID: 18978154.
纯度:≥98%
CAS:146662-42-2