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SR1555
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1386439-51-5
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

SR1555 is an inverse agonist of RORgamma which suppresses TH17 differentiation and stimulated iTreg cells, repressing the expression of RORgamma while leading to increased expression of FGF21 and adipoQ, thereby reducing body weight and improving insulin sensitivity. References: Chang MR, He Y, Khan TM, Kuruvilla DS, Garcia-Ordonez R, Corzo CA, Unger TJ, White DW, Khan S, Lin L, Cameron MD, Kamenecka TM, Griffin PR. Antiobesity Effect of a Small Molecule Repressor of RORγ. Mol Pharmacol. 2015 Jul;88(1):48-56. doi: 10.1124/mol.114.097485. Epub 2015 Apr 22. PubMed PMID: 25904554; PubMed Central PMCID: PMC4468634.

纯度:≥98%

CAS:1386439-51-5