GV196771A is an NMDA receptor/glycine site antagonist. GV196771A attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice. References: Polli JW, Baughman TM, Humphreys JE, Jordan KH, Mote AL, Webster LO, Barnaby RJ, Vitulli G, Bertolotti L, Read KD, Serabjit-Singh CJ. The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters. Drug Metab Dispos. 2004 Jul;32(7):722-6. PubMed PMID: 15205387.
纯度:≥98%
CAS:166974-22-7