GSK-356278 is a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that displays anxiolytic and cognition-enhancing effects. GSK-356278 has the ability to elevate cAMP in various cell types of the central nervous system. References: Rutter AR, Poffe A, Cavallini P, Davis TG, Schneck J, Negri M, Vicentini E, Montanari D, Arban R, Gray FA, Davies CH, Wren PB. GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species. J Pharmacol Exp Ther. 2014 Jul;350(1):153-63. doi: 10.1124/jpet.114.214155. Epub 2014 Apr 30. PubMed PMID: 24784567.

纯度：≥98%

CAS：720704-34-7