GRC-6211 is an orally bioavailable specific TRPV1 antagonist which decreases bladder overactivity and noxious bladder input in cystitis animal models. References: Santos-Silva A, Charrua A, Cruz CD, Gharat L, Avelino A, Cruz F. Rat detrusor overactivity induced by chronic spinalization can be abolished by a transient receptor potential vanilloid 1 (TRPV1) antagonist. Auton Neurosci. 2012 Jan 26;166(1-2):35-8. doi: 10.1016/j.autneu.2011.09.005. Epub 2011 Oct 28. PubMed PMID: 22037502.
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CAS:1166398-35-1