TAS05567 is a potent and selective orally bioavailable Syk inhibitor, which inhibits BCR-dependent cell signaling as well as FcR-mediated immune responses. References: Hayashi H, Kaneko R, Demizu S, Akasaka D, Tayama M, Harada T, Irie H, Ogino Y, Fujino N, Sasaki E. TAS05567, a Novel Potent and Selective Spleen Tyrosine Kinase Inhibitor, Abrogates Immunoglobulin-Mediated Autoimmune and Allergic Reactions in Rodent Models. J Pharmacol Exp Ther. 2018 Jul;366(1):84-95. doi: 10.1124/jpet.118.248153. Epub 2018 May 4. PubMed PMID: 29728446.
纯度:≥98%
CAS:1429038-15-2