Galphimine B is a nor-seco-triterpenoid from Galphimia glauca. Sedative effect, has Sedative effect. Galphimine B modulates synaptic transmission on dopaminergic ventral tegmental area neurons. GB modifies synaptic activity on dopaminergic VTA neurons by a non-GABAergic mechanism. References: Jiménez-Ferrer E, Herrera-Ruiz M, Ramírez-García R, Herrera-Arellano A, Tortoriello J. Interaction of the natural anxiolytic Galphimine-B with serotonergic drugs on dorsal hippocampus in rats. J Ethnopharmacol. 2011 Sep 1;137(1):724-9. doi: 10.1016/j.jep.2011.06.029. Epub 2011 Jul 1. PubMed PMID: 21742023.
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CAS:149199-48-4