FR-168888 is a new Na+/H+ exchange inhibitor. FR168888 has a strong inhibitory effect on Na+/H+ exchange and that treatment with FR168888 can protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations. References: Zhu BM, Miyamoto S, Kamiya K, Komori S, Hashimoto K. Inhibitory effects of pre-ischemic and post-ischemic treatment with FR 168888, a Na+/H+ exchange inhibitor, on reperfusion-induced ventricular arrhythmias in anesthetized rat. Jpn J Pharmacol. 2002 Jan;88(1):93-9. PubMed PMID: 11855683.
纯度:≥98%
CAS:168620-46-0