PFE-360, formerly known asd PF-06685360, is a potent and selective inhibitor of LRRK2 kinase. References: Andersen MA, Christensen KV, Badolo L, Smith GP, Jeggo R, Jensen PH, Andersen KJ, Sotty F. Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation. Neurobiol Dis. 2018 Aug;116:13-27. doi: 10.1016/j.nbd.2018.04.011. Epub 2018 Apr 20. PubMed PMID: 29680709.
纯度:≥98%
CAS:1527475-61-1