Mesoxalic acid is a dicarboxylic acid and a ketonic acid. It blocks RT translocation. Hot spots for inhibition occur at template positions with a bias toward pre-translocation. References: Bernatchez JA, Paul R, Tchesnokov EP, Ngure M, Beilhartz GL, Berghuis AM, Lavoie R, Li L, Auger A, Melnyk RA, Grobler JA, Miller MD, Hazuda DJ, Hecht SM, Gotte M. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. J Biol Chem. 2015 Jan 16;290(3):1474-84. doi: 10.1074/jbc.M114.614305. Epub 2014 Oct 29. PubMed PMID: 25355312; PubMed Central PMCID: PMC4340395.

纯度：≥98%

CAS：473-90-5