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TG693
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TG693图片
CAS NO:885272-55-9
规格:≥98%
包装与价格:
包装价格(元)
100mg电议
500mg电议
1g电议

产品介绍

TG693 is a novel, potent, orally bioavailable, selective, ATP-competitive Cdc2-like Kinases (CLK1) inhibitor with IC50 of 112.6 nM. It also potently inhibits haspin activity and weakly inhibits DYRK kinases in a panel of 313 recombinant kinases; promotes the skipping of the endogenous mutated exon 31 in DMD patient-derived cells and increases the production of the functional exon 31-skipped dystrophin protein; inhibits the phosphorylation of CLK1 substrate serine/arginine-rich proteins and modulates pre-mRNA splicing in the skeletal muscle in mice.

纯度:≥98%

CAS:885272-55-9